Bouaicha
Fakultäten » Medizinische Fakultät » Universitätsklinik Balgrist und Schweizerisches Paraplegikerzentrum » Orthopädie » Prof. Dr. Christian Gerber » Bouaicha
Current research project
| Title / Titel | Early Procalcitonin serum level after 1) minimal invasive hip 2) total knee and 3) total shoulder-replacement surgery | ||||||||
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| Abstract (PDF, 14 KB) | |||||||||
| Summary / Zusammenfassung | The literature demonstrates procalcitonin to be a specific marker for bacterial infections (Assicot et al. Lancet 1993 and many others). The serum procalcitonin is not frequently used in the daily clinical business yet. The clinicians are not seldom in doubt if an increased CRP, ESR or WBC in the early postoperative phase after a total hip, knee or shoulder replacement are the manifestations of an early bacterial infection or the signs of an unspecific postoperative inflammation reaction. In some recently published studies (Jebali et al. Anesthesiology 2007/ Bottner et al. JBJS Br. 2007) the authors described procalcitonin to be useful in 1) the recognition of early infections after cardial surgery, and 2) to be of high specifity in the diagnosis of late periprosthetic infections following total joint replacement. There is not data available yet on the early postoperative procalcitonin serum level after standardized joint replacements such as minimally invasive THR, TKR and TSR. The aim of our study is to prospectively measure the physiological serum levels of procalcitonin from preoperative until 3 months postoperative in comparison with the traditional inflammation parameters (CPR, ESR and WBC) in patients undergoing total joint replacement. |
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| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
Others |
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| Duration of Project / Projektdauer | Jan 2009 to May 2012 |